This chapter explores the universal quest for happiness by contrasting two distinct visions: modern transhumanism and classical Aristotelian ethics. Transhumanism seeks to overcome human limitations through technology, aiming for “super” states of longevity, intelligence, and well-being, effectively pursuing a technologically-achieved immortality and bliss. In contrast, Aristotle’s concept of eudaimonia defines happiness not as a passive state but as a life of virtuous activity in accordance with reason. For Aristotle, human flourishing is an internal process of cultivating moral and intellectual excellence over a complete, finite life. While both frameworks value happiness and intellect, they diverge fundamentally on their means—external technology versus internal character—and on the very nature of human existence, with one seeking to transcend our given nature and the other seeking to perfect it.